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AMGN
Amgen Inc.
Summary
Business
Earnings Call
Valuation
Profitability
Financial Health
Yearly Return 10Y annualized return is positive but below market average at 6.2% per year
Earnings Expectations AMGN has met or exceeded earnings expectations in most recent quarters (9/10)
Positive Strong Return on Equity
Positive Strong Gross Profit Margin
Positive Decent Operating Profit Margin
Positive Adequate Current Ratio
Positive Strong Cash Position
Positive Strong Revenue Growth
Positive Diverse and Robust Product Portfolio
Positive Strong Pipeline and R&D Investments
Positive Expanding Market Opportunities
Positive Innovative Pipeline Advancements
Negative High Price-to-Earnings Ratio
Negative Elevated Price-to-Sales Ratio
Negative Low Net Profit Margin
Negative High Debt Levels
Negative Low Interest Coverage
Negative Pricing Pressures
Negative Upcoming Patent Expiry Risks
Negative Competitive Pressures in Obesity Market
Negative Regulatory Challenges

Overall, Amgen demonstrates strong business quality with robust revenue growth, a diverse product portfolio, and significant R&D investments. However, it faces challenges such as pricing pressures and patent expirations. Future prospects are bolstered by expanding opportunities and innovation in its pipeline, although competition in certain markets remains a concern.

Analysis Date: February 4, 2025
Last Updated: March 11, 2025

+83%
+6.2% per year

Past performance does not guarantee future results. The data presented is indicative and may not be updated in real-time.

Country US
Exchange NASDAQ
Industry Drug Manufacturers - General
Sector Healthcare
Market Cap $139.48B
CEO Mr. Robert A. Bradway

Amgen Inc. is a company that makes medicines to help treat various health problems, such as cancer, bone diseases, and heart issues. They create products like Enbrel for arthritis and Neulasta to protect cancer patients from infections. Amgen works with doctors and hospitals to provide these treatments to patients all around the world. Founded in 1980 and based in California, Amgen is dedicated to improving people's health through their innovative therapies.

Streams of revenue

Prolia: 15%
ENBREL: 12%
Repatha (evolocumab): 8%
Otezla: 8%
XGEVA: 8%
TEPEZZA: 7%
Nplate: 7%
EVENITY: 6%
Kyprolis: 6%
Aranesp: 5%
BLINCYTO: 5%
KRYSTEXXA: 5%
Vectibix: 4%
TEZSPIRE: 4%

Geographic Distribution

UNITED STATES: 73%
Non-US: 27%

Core Products

No core products data available

Business Type

No business type data available

Competitive Advantages

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Strong R&D Pipeline Amgen's commitment to research and development enables the continuous introduction of innovative therapies, maintaining a competitive edge in the biotechnology sector.
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Regulatory Expertise Deep knowledge and experience in navigating complex regulatory environments facilitate quicker approvals and market entry for new products.
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Strategic Partnerships Collaborations with major pharmaceutical companies enhance Amgen's capabilities in drug development and broaden its market reach.
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Robust Intellectual Property Strong patent protections for its innovative drugs protect against generic competition and sustain long-term profitability.
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Established Product Portfolio A diverse range of well-established products like Enbrel and Neulasta provides a stable revenue stream and market presence.

Key Business Risks

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Patent Expiry Expiration of patents on key products can lead to generic competition and reduced profitability.
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Market Competition Intense competition from other pharmaceutical companies can affect market share and pricing strategies.
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R&D Pipeline Risks Failures in drug development or clinical trials can lead to significant financial losses and impact future growth.
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Regulatory Compliance Changes in healthcare regulations and compliance requirements can impact product approvals and market access.
πŸ“¦
Supply Chain Disruptions Disruptions in the supply chain can affect the manufacturing and distribution of products, leading to revenue loss.

Trailing Twelve Months (TTM) values provide a view of the company's performance over the last year.

Graham Value Metrics

Benjamin Graham's value investing approach focuses on finding stocks with a significant margin of safety between their intrinsic value and market price.

Intrinsic Value

Estimated fair value based on Graham's formula

$94.59

Current Market Price: $292.59

IV/P Ratio: 0.32x (>1.0 indicates undervalued)

Margin of Safety

Gap between intrinsic value and market price

-209.0%

Graham recommended a minimum of 20-30% margin of safety

Higher values indicate a greater potential discount to fair value

Graham Criteria Checklist

Benjamin Graham's value investing checklist for AMGN

Yes Positive earnings (5+ years)
Yes Dividend history (5+ years)
No P/E ratio ≀ 20 (38.91)
No P/B ratio ≀ 1.5 (27.08)
No Current ratio β‰₯ 2.0 (1.26x)
No Long-term debt < Net current assets (9.53x)
No Margin of safety (-209.0%)
No AMGN does not meet all Graham criteria

ROE: 67.18409921563796

ROA: None

Gross Profit Margin: 61.53063666826233

Net Profit Margin: 12.236716132120632

Trailing Twelve Months (TTM) values provide a view of the company's performance over the last year.

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About Profitability Metrics

Profitability metrics measure a company's ability to generate earnings relative to its revenue, operating costs, and other relevant metrics. Higher values generally indicate better performance.

Return on Equity (ROE)

Measures how efficiently a company uses its equity to generate profits

67.18%

10% 15%

Higher values indicate better returns for shareholders

TTM (as of 2025-04-30)

Gross Profit Margin

Percentage of revenue retained after accounting for cost of goods sold

61.53%

20% 40%

Higher values indicate better efficiency in production

TTM (as of 2025-04-30)

Net Profit Margin

Percentage of revenue retained after accounting for all expenses

12.24%

8% 15%

Higher values indicate better overall profitability

TTM (as of 2025-04-30)

Strong Gross Profit Margin

61.41%
Gross Profit Margin

The gross profit margin of 61.41% indicates that the company retains a significant portion of revenue as profit after accounting for the cost of goods sold.

Decent Operating Profit Margin

21.47%
Operating Profit Margin

An operating profit margin of 21.47% shows that the company is managing its operating expenses well relative to its revenue.

Low Net Profit Margin

12.28%
Net Profit Margin

The net profit margin of 12.28% suggests that, while gross margins are strong, overall profitability is limited after all expenses are considered.

About Financial Health Metrics

Financial health metrics assess a company's ability to meet its financial obligations and its overall financial stability.

Debt to Equity Ratio

Total debt divided by total equity

10.23x

1.0x 2.0x

Lower values indicate less financial leverage and risk

Less than 1.0 is conservative, 1.0-2.0 is moderate, >2.0 indicates high risk

Q4 2024

Current Ratio

Current assets divided by current liabilities

1.26x

1.0x 2.0x

Higher values indicate better short-term liquidity

Less than 1.0 is concerning, 1.0-2.0 is adequate, greater than 2.0 is good

Q4 2024

Adequate Current Ratio

1.26
Current Ratio

A current ratio of 1.26 indicates that the company has enough current assets to cover its current liabilities, suggesting good short-term financial health.

Strong Cash Position

$22.15
Cash Per Share

With cash per share at $22.15, the company has a solid cash position to support operations and investments.

High Debt Levels

10.23
Debt-to-Equity Ratio
65.44%
Debt-to-Assets Ratio

The debt-to-equity ratio of 10.23 and debt-to-assets ratio of 65.44% indicate high reliance on debt, which can increase financial risk.

Low Interest Coverage

2.27
Interest Coverage Ratio

An interest coverage ratio of 2.27 suggests the company may struggle to meet interest obligations, indicating potential financial stress.

Meeting Expectations

9 /10

Higher values indicate better execution and credibility

Recent Results

Beat earnings
2025-02-04 +5.4%
Beat earnings
2024-10-30 +9.2%
Missed earnings
2024-08-06 -0.2%
Beat earnings
2024-05-02 +2.1%
Beat earnings
2024-02-06 +2.6%
Beat earnings
2023-10-31 +6.7%
Beat earnings
2023-08-03 +12.6%
Beat earnings
2023-04-27 +3.4%
Beat earnings
2023-01-31 +1.2%
Beat earnings
2022-11-03 +5.9%

EPS

5.04
Estimated
5.31
Actual
+5.36%
Difference

Strong Revenue Growth

$33.4 billion
2024 Total Revenues
19% year-over-year
Product Sales Growth

Amgen reported a 19% growth in product sales for the year, fueled by strong execution across its therapeutic areas. The company has a solid track record of revenue growth, achieving mid-single-digit growth over the past decade, despite facing competition from biosimilars.

Diverse and Robust Product Portfolio

14
Blockbuster Products
$2.2 billion
Repatha 2024 Sales
$1.6 billion
EVENITY 2024 Sales

Amgen exited 2024 with 14 medicines each generating over $1 billion in annual sales. This includes key products like Repatha and EVENITY, which are positioned for significant growth due to their large addressable markets.

Strong Pipeline and R&D Investments

$5.9 billion
2024 R&D Spend

Amgen is investing heavily in R&D, with a 25% increase in spending year-over-year, focusing on innovative products across various therapeutic areas. This positions the company for future growth and market leadership.

Pricing Pressures

Mid-single digits
Expected Price Erosion for Repatha

Amgen faces declining net prices and potential losses of exclusivity for some products. For example, the company anticipates continued price erosion for Repatha, albeit at a reduced rate.

Upcoming Patent Expiry Risks

Upcoming
Denosumab Patent Expiry

The upcoming patent expiration for denosumab poses a risk to revenue streams, which could affect the company's overall market position.

Expanding Market Opportunities

100 million
Potential Patients for Repatha
7 countries in 2025
TEPEZZA New Market Launches

Amgen has significant growth prospects with multiple products set to address large unmet needs, such as Repatha's expansion into primary prevention and the launch of TEPEZZA in additional countries.

Innovative Pipeline Advancements

Multiple
Number of Phase III Trials Initiated in 2025

Amgen's pipeline includes promising therapies like MariTide and olpasiran, which are expected to progress into Phase III trials in 2025. This innovation could enhance Amgen's market position in key therapeutic areas.

Competitive Pressures in Obesity Market

1-2
Obesity Assets with Development Issues

While the company is optimistic about MariTide, there have been setbacks in obesity assets, indicating potential vulnerabilities in this competitive field.

Regulatory Challenges

Ongoing
Regulatory Challenges

Navigating regulatory and political changes poses challenges that could impact product approvals and market access, potentially affecting sales growth.

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